Publications
41

Cabrera-Pardo, J.R.; Chai, D.I.; Kozmin, S.A. Silver-Promoted Benzannulations of Siloxyalkynes with Pyridinium and Isoquinolinium Salts. Adv. Synth. Catal. 2013, 355, 2495-2498.

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40

Liu, S.; Scotti, J.S.; Kozmin, S.A. Emulating the Logic of Monoterpenoid Alkaloid Biogenesis to Access a Skeletally Diverse Chemical Library. J. Org. Chem. 2013, 78, 8645-8654.

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39

Cabrera-Pardo, J.R.; Chai, D.I.; Liu, S.; Mrksich, M.; Kozmin, S.A. Label-Assisted Mass Spectrometry for the Acceleration of Reaction Discovery and Optimization. Nat. Chem. 2013, 5, 423-427.

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38

Cui, J.; Chai, D.I.; Miller, C.; Hao, J.; Thomas, C.; Wang, J.Q.; Scheidt, K.A.; Kozmin, S.A. Assembly of Four Diverse Heterocyclic Libraries Enabled by Prins Cyclization, Au-Catalyzed Enyne Cycloisomerization, and Automated Amide Synthesis. J. Org. Chem. 2012, 77, 7435-7470.

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37

Türkmen, Y.E.; Montavon, T.J.; Kozmin, S.A.; Rawal, V.H. Silver-Catalyzed Formal Inverse Electron-Demand Diels-Alder Reaction of 1,2-Diazines and Siloxy Alkynes. J. Am. Chem. Soc. 2012, 134, 9062-9065.

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36

Montavon, T.J.; Li, J.; Cabrera-Pardo, J.R.; Mrksich, M.; Kozmin, S.A. Three Component Reaction Discovery Enabled by Mass Spectrometry of Self-Assembled Monolayers. Nat. Chem. 2012, 4, 45-51.

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35

Pronin, S.V.; Martinez, A.; Kuznedelov, K.; Severinov, K.; Shuman, H.A.; Kozmin, S. A. Chemical Synthesis Enables Biochemical and Antibacterial Evaluation of Streptolydigin Antibiotics. J. Am. Chem. Soc. 2011, 133, 12172-12184.

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34

Cui, J.; Hao, J.; Ulanovskaya, O. A.; Dundas, J.; Liang, J.; Kozmin, S. A. Creation and Manipulation of Common Functional Groups En Route to a Skeletally Diverse Chemical Library. PNAS. 2011, 17, 6763-6768.

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33

Ulanovskaya, O. A.; Cui, J.; Kron, S. J.; Kozmin, S. A. A Pairwise Chemical Genetic Screen Identifies New Inhibitors of Glucose Transport. Chemistry & Biology. 2011, 18, 222-230.

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32

Pronin, S.V.; Kozmin, S.A. Synthesis of Streptolydigin, a Potent Bacterial RNA Polymerase Inhibitor. J. Am. Chem. Soc. 2010, 132, 14394-14396.

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31

Cui, J.; Matsumoto, K.; Wang, C. Y.; Peter, M. E.; Kozmin, S. A. Synthesis of High-Purity Chemical Library Reveals a Potent Inducer of Oxidative Stress. ChemBioChem. 2010, 11, 1224-1227.

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30

Rizvi, S. A.; Liu, S.; Chen, Z.; Skau, C.; Pytynia, M.; Kovar, D. R.; Chmura, S. J.; Kozmin, S. A. Rationally Simplified Bistramide Analog Reversibly Targets Actin Polymerization and Inhibits Cancer Progression in Vitro and in Vivo. J. Am. Chem. Soc. 2010, 132, 7288-7290.

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29

Schramm, M. P.; Shubinets, V. Kozmin, S. A. Preparation and [2+2] Cycloaddition of 1-Triisopropylsiloxy-1-hexyne with Methyl Crotonate:  3-Butyl-4-methyl-2-triisopropylsiloxy-cyclobut-2-enecarboxylic Acid Methyl Ester. Org. Synth. 2010, 87, 253-263.

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28

Lee, H.; Suzuki, M.; Cui, J.; Kozmin, S. A. Synthesis of an Azide-Tagged Library of 2,3-Dihydro-4-quinolones J. Org. Chem. 2010, 75, 1756-1759.

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27

Sun, J.; Keller, V. A.; Meyer, S. T.; Kozmin, S. A. Silver-Catalyzed Aldehyde Olefination Using Siloxy Alkynes. Adv. Synth. Catal. 2010, 352, 839-842.

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26

Rizvi, S. A.; Neidt, E. M.; Cui, J.; Feiger, Z.; Gardel, M. L.; Kozmin, S. A.; Kovar, D. R. Identification of a Small Molecule Inhibitor of Formin-Mediated Actin Assembly. Chem. Biol. 2009, 11, 1158-1168.

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25

Ulanovskaya, O. A.; Janjic, J.; Suzuki, M.; Sabharwal, S. S.; Schumacker, P. T.; Kron,S. J.; Kozmin, S. A. Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Nature Chem. Biol. 2008, 4, 418-424.

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24

Rizvi, S. A.; Courson D. S.; Keller, V. A.; Rock, R. S.; Kozmin, S. A. The dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modification. Proc. Natl. Acad. Sci. 2008, 105, 4088-4092.

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23

Matsumoto, K.; Kozmin, S. A. Eight-Step Synthesis of Routiennocin. Adv. Synth. Catal. 2008, 350, 557-560.

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22

Marjanovic, J.; Kozmin, S. A. Spirofungin A: Stereoselective Synthesis and Inhibition of Isoleucyl-tRNA Synthetase. Angew. Chem. Int. Ed. 2007, 46, 8854-8857.

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21

Zhang, L.; Sun, J.; Kozmin S. A. Gold and Platinum Catalysis of Enyne Cycloisomerization. Adv. Synth. Catal. (Special Issue), 2006, 348, 2271-2296.

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20

Zhang, L.; Sun, J.; Kozmin, S. A. Brønsted Acid-Promoted Cyclizations of Siloxy Alkynes with Unactivated Arenes, Alkenes and Alkynes. Tetrahedron (Symposium in Print), 2006, 62, 11371-11380.

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19

Sun, J.; Kozmin, S. A. Silver-Catalyzed Hydroamination of Siloxy Alkynes. Angew. Chem. Int. Ed. 2006, 45, 4991-4993.

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18

Sun, J.; Conley, M.; Zhang, L.; Kozmin, S. A. Gold and Platinum-Catalyzed Cycloisomerizations of 1,5-Enynes to Cyclohexadienes with a Broad Alkyne Scope. J. Am. Chem. Soc. 2006, 128, 9705-9710.

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17

Rizvi, S.; Tereshko, V.; Kossiakoff, A. A.; Kozmin, S. A. Structure of Actin-Bistramide A Complex at 1.35 A Resolution. J. Am. Chem. Soc. 2006, 128, 3882-3883.

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16

Statsuk, A. V.; Bai, R.; Baryza, J. L.; Verma, V. A.; Hamel, E.; Wender, P. A.; Kozmin, S. A. Actin is the Primary Cellular Receptor of Bistramide A. Nature Chem. Biol. 2005, 1, 383-388.

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15

Sun, J.; Kozmin, S. A. Brønsted Acid-Promoted Cyclizations of 1-Siloxy-1,5-diynes. J. Am. Chem. Soc. 2005, 127, 13512-13513.

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14

Wang, Y.; Janjic, J.; Kozmin, S. A. Synthesis of Leucascandrolide A. Pure Appl. Chem. 2005, 77, 1161-1169. (invited submission, IUPAC ICOS-15, Nagoya, Japan).

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13

Zhang, L.; Kozmin, S. A. Gold-Catalyzed Assembly of Heterobicyclic Systems. J. Am. Chem. Soc. 2005, 127, 6962-6963.

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12

Zhang, L.; Kozmin, S. A. Gold-Catalyzed Cycloisomerizations of Siloxy Enynes to Cyclohexadienes. J. Am. Chem. Soc. 2004, 126, 11806-11807.

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11

Zhang, L.; Kozmin, S. A. Brønsted Acid-Promoted Cyclizations of Siloxyalkynes with Arenes and Alkenes. J. Am. Chem. Soc. 2004, 126, 10204-10205.

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10

Statsuk, A. V.; Liu, D.; Kozmin, S. A. Synthesis of Bistramide A. J. Am. Chem. Soc. 2004, 126, 9546-9547.

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9

Sweis, R.; Schramm, M. P.; Kozmin, S. A. Silver-Catalyzed [2+2] Cycloadditions of Siloxyalkynes. J. Am. Chem. Soc. 2004, 126, 7442-7443.

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8

Reddy, D. S.; Kozmin, S. A. Efficient and General Approach to Eremophilanes Using Siloxyalkyne-Alkene Metathesis. J. Org. Chem. 2004, 69, 4860-4862.

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7

Kozmin, S. A.; Liu, D. Breaking the Symmetry of Silacyclic Templates to Assemble Pinolidoxin and Herbarumin I. Strategies and Tactics in Organic Synthesis, Ed. Harmata, M. 2004, Vol 5, 87-110.

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6

Kozmin, S. A.; Wang, Y. A Three-Dimensional Array for Multiparallel Synthesis. Angew. Chem. Int. Ed. Engl. 2003, 42, 903-905.

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5

Wang, Y.; Janjic, J.; Kozmin, S. A. Synthesis of Leucascandrolide A via a Spontaneous Macrolactolization. J. Am. Chem. Soc. 2002, 124, 13670-13671.

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4

Liu, D.; Kozmin, S. A. Synthesis of Pinolidoxin: Divergent Synthetic Strategy Exploiting a Common Silacyclic Precursor. Org. Lett. 2002, 4, 3005-3007.

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3

Liu, D.; Kozmin, S. A. Catalytic Enantioselective Isomerization of Silacyclopentene Oxides: New Strategy for Stereocontrolled Assembly of Acyclic Polyols. Angew. Chem. Int. Ed. Engl. 2001, 40, 4757-4759.

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2

Schramm, M. P.; Reddy, D. S.; Kozmin, S. A. Siloxyalkyne-Alkene Metathesis: Rapid Access to Highly Functionalized Enones. Angew. Chem. Int. Ed. Engl. 2001, 40, 4274-4277.

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1

Kozmin, S. A. Efficient Stereochemical Relay en Route to Leucascandrolide A. Org. Lett. 2001, 3, 755-758.

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